Rui Zhao, M viagra liquid .D., George A. Comes after, M.R.C.P., M.R.C.Route., Philip A. Beer, M.R.C.P., M.R.C.Route., Linda M. Scott, Ph.D., Brian J.P. Huntly, M.R.C.P., M.R.C.Route., Anthony R. Green, F.R.C.Path., F.Med.Sci., and Denis R. Alexander, Ph.D.: Inhibition of the Bcl-xL Deamidation Pathway in Myeloproliferative Disorders Chronic myeloid leukemia and polycythemia vera are clonal myeloproliferative disorders that are associated with the activation of distinct tyrosine kinases, the BCR-ABL fusion kinase1 and the Janus tyrosine kinase 2 mutation,2,3 respectively. In both disorders, patients usually present with chronic disease, which is readily controlled. However, for reasons that are unclear, a risk is carried by both illnesses of progression to a blastic phase resembling acute leukemia that resists further therapy.