To check for other conditions, the doctor might order blood checks, or an X-rays. Treatment Most cases of AN only involve changes in skin thickening and color of epidermis, and there is no set treatment for it. For most kids, AN will demand no treatment at all; for a few, the dark skin will fade on its own. For situations of AN where an underlying cause is determined, treating the cause could make the dark patches of skin fade or disappear entirely. This can mean ceasing any medications that could be causing the nagging problem or treating any health issues. For most kids, the best treatment for AN is to keep a healthy weight and get a lot of exercise. Encourage your son or daughter to eat an excellent diet and make healthy lifestyle choices.Methods Patients Patients between the ages of 18 and 75 years who all were classified seeing that having active psoriatic arthritis based on the Classification Requirements for Psoriatic Arthritis 25 with 3 or more tender joints and 3 or more swollen joints were eligible for the study. Various other exclusion criteria included latest infection , recurrent infections, main chronic inflammatory or connective-tissue disease, significant systemic disease clinically, or a brief history of cancer within the past 5 years. Unfavorable test results for tuberculosis had been required. All patients provided written informed consent. Study Design The study, that was conducted at 29 sites in the United Canada and Says, was a randomized, double-blind, placebo-controlled, 12-week trial, that was accompanied by an open-label extension trial .