For instance, when working with a ladder, never stand on the top rung,’ Dr. Patrick Osborn, an American Academy of Orthopaedic Surgeons spokesman and orthopedic trauma doctor, said in an AAOS news release. Last year in the usa, a lot more than 500,000 ladder-related injuries and more than 42,000 rake-related injuries were treated by doctors, the AAOS said. To stay safe whilst getting your yard and home clean, some advice emerges by the AAOS. Use a rake that’s suitable for your elevation and weight, and have equipment such as leaf blowers serviced before you use them this fall.II. Masitinib simply because first-line treatment of advanced GIST Two other presentations were shipped also, one reporting on the 5-year follow-up data from a stage II clinical study of masitinib in the first-range treatment of advanced or metastatic GIST locally, and a related presentation describing the ongoing phase III study for this indication. The poster communication Masitinib in imatinib-naive advanced gastrointestinal stromal tumor : Five-year follow-up of the French Sarcoma Group stage II trial , shipped by Dr Axel Le Cesne , reported on the most recent data from a multicenter, open label, phase II study, evaluating safety and efficacy of masitinib as a first-line treatment of advanced GIST. Median overall survival in masitinib comes even close to that of favorably imatinib in individuals with KIT exon 11 mutation especially subpopulation.