Headaches in general usually are caused by disorders such as for example migraines or tension-type head aches. But headaches can also be secondary to other conditions, and some of these conditions could be life-threatening. Almost all headaches associated with sex are benign. However in a small percent of cases, these head aches could be due to a serious underlying condition, such as a hemorrhage, mind aneurysm, stroke, cervical artery dissection or subdural hematoma. So we recommend that patients undergo a thorough neurological evaluation to eliminate secondary causes, which can be life-threatening, Biller said.Noyan Gokce, MD, associate professor of medication at BUSM, and Melissa Farb, PhD, a postdoctoral fellow at BUSM, also collaborated on the study. Diets that are high in excess fat and cholesterol induce adjustments in how the body regulates blood sugar levels. Exercise induces an increased production adenosine, a metabolite made by cells naturally. A2bAR, a occurring proteins receptor within the cell membrane normally, is activated by adenosine. This receptor is known to play an important role in regulating inflammation, which is associated with type 2 diabetes and obesity.